Patients choosing PRP (Platelet-Rich Plasma) often ask the golden question: "How long will the relief last?"

Unlike a steroid shot that wears off in weeks, PRP is a biological treatment designed for longer-term healing.

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The Typical Duration: 6 to 12 Months

For most patients with mild to moderate arthritis (Stages 1-3), a single course of PRP provides significant pain relief for 6 months to 1 year.

Some "super-responders" experience relief for up to 18-24 months.

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Factors That Affect Longevity

Why does it last longer for some than others?

1. Severity of Arthritis

• Early Stage (Mild): Best results, longest duration.
• Late Stage (Severe): Shorter duration. If you have bone-on-bone friction, the mechanical wear eventually overpowers the biological healing.

2. Your Overall Health

Since PRP uses your blood, the quality of your platelets matters. Patients who are healthy, non-smokers, and have good nutrition tend to have more potent plasma.

3. Post-Injection Rehabilitation

Patients who combine PRP with physiotherapy to strengthen their legs get longer-lasting results because the muscles protect the joint.

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The "Booster" Strategy

PRP is not a one-time vaccine. It is a maintenance therapy.

• Most doctors recommend a yearly maintenance injection to keep the inflammation down and the joint healthy.
• It is safe to repeat as often as needed because it is natural.

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Takeaway

PRP is a marathon, not a sprint. While it takes time to kick in (4-6 weeks), the relief is durable and natural.

Expect about a year of relief, and plan for maintenance to keep your knees pain-free.